Naturally Occurring Rhamnopyranosides as Anticancer Agents: Molecular Docking and ADMET Study

After heart disease, cancer continues to be the second most prevalent cause of death in USA. Several chemotherapeutic treatments (drugs) are available for that use powerful chemicals kill body's rapidly proliferating cells. However, recent research disclosed many clinically viable anticancer drugs have been developed with help originating from plants. A number phytochemicals isolated plants possess rhamnopyranoses and some them acyl rhamnopyranoses. Encouragingly, such compounds were reported their cell proliferation migration inhibition activities against invasive human triple-negative breast In this study, four naturally occurring rhamnopyranose esters checked three cancer-related proteins (PDB IDs: 3TJM, 4OAR, 5FGK) via molecular docking. Rhamnose 3-6 showed better binding energy compared related standard hospitals. Compound 6 was found highly potential all (-8.5 -11.3 kcal/mol). ADMET studies also discussed respect. This study indicated natural could used stop spreading cells like other sugar fatty acid (SFAEs).